Essentials Pharmaceutical Chemistry

Product Description

It covers the core information required by pharmacy students to understand the action of modern drugs on the human body.The third edition is larger than the previous edition and includes a new chapter on licensing of drugs and medicines which describes the make up and function of important committees such as the Commission of Human Medicines and the British Pharmacopoeia Commission. This includes material that is within the public domain and explains the process of getting a drug to market.The majority of the chapters include more worked examples/tutorial examples and the chapter on Analytical spectroscopy has been updated to include "qualitative" spectroscopic methods especially NMR, mass spectroscopy and some IR and the chapter on Stability of drugs and medicines has been updated to include a major section on "prodrugs" which are inactive compounds designed to decompose within the body to release the active moiety.

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Green Chemistry in the Pharmaceutical Industry

Peter Dunn, Andrew Wells, Michael T. Williams, Green Chemistry in the Pharmaceutical Industry

Wiley-VCH | 2010 | ISBN: 3527324186 | 388 pages | File type: PDF | 5,8 mb 

Edited by three of the world's leading pharmaceutical scientists, this is the first book on this important and hot topic, containing much previously unpublished information. As such, it covers all aspects of green chemistry in the pharmaceutical industry, from simple molecules to complex proteins, and from drug discovery to the fate of pharmaceuticals in the environment. Furthermore, this ready reference contains several convincing case studies from industry, such as Taxol, Pregabalin and Crestor, illustrating how this multidisciplinary approach has yielded efficient and environmentally-friendly processes. Finally, a section on technology and tools highlights the advantages of green chemistry.

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Fundamentals of Analytical Chemistry

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FUNDAMENTALS OF ANALYTICAL CHEMISTRY, EIGHTH EDITION is known for its readability combined with a systematic, rigorous approach that characterizes this classic text. Extensive coverage of the principles and practices of quantitative chemistry ensures suitability for chemistry majors. These award-winning authors include applications throughout industry, medicine, and all the sciences. The text's new design and wealth of new photographs by renowned chemistry photographer Charlie Winters serve to reinforce student learning through dynamic visuals. Reflecting the increased emphasis of spreadsheets as a tool in analytical chemistry, this new edition adds an additional chapter, new problems and a new supplement, EXCEL® APPLICATIONS FOR ANALYTICAL CHEMISTRY, that integrate this important aspect of the study of analytical chemistry into its already rich pedagogy. In addition, the INTERACTIVE ANALYTICAL CHEMISTRY CD-ROM, packaged FREE with every new text, enhances conceptual understanding through hands-on integrated multimedia interactivity.

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Burger's Medicinal Chemistry And Drug Discovery, Volume 6, Nervous System Agents, 6th Edition

Book Summary of Burger's Medicinal Chemistry And Drug Discovery, Volume 6, Nervous System Agents, 6th Edition

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This is Volume 6: Nervous System Agents, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Alzheimer's Disease: Search for Therapeutics, Cognition Enhancers and Drugs to Treat Eating and Body Weight Disorders. 

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Burger's Medicinal Chemistry And Drug Discovery, Volume 5, Chemotherapeutic Agents, 6th Edition

Burger's Medicinal Chemistry And Drug Discovery, Volume 5, Chemotherapeutic Agents, 6th Edition

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This is Volume 5: Chemotherapeutic Agents, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Molecular Biology of Cancer, Synthetic Anti-angiogenic Agents and Selective Toxicities. 

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Burger's Medicinal Chemistry And Drug Discovery, Volume 4, Autocoids, Diagnostics, And Drugs From New Biology, 6th Edition

Book Summary of Burger's Medicinal Chemistry And Drug Discovery, Volume 4, Autocoids, Diagnostics, And Drugs From New Biology, 6th Edition

Product description

This is Volume 4: Autocoids, Diagnostics, and Drugs from New Biology, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Peptide and Protein Hormones, Peptide Neurotransmitters, and Therapeutic Agents, Vitamins and SNPs: Single Nucleotide Polymorphisms and Pharmacogenomics. 

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Burger's Medicinal Chemistry And Drug Discovery, Volume 3 , Cardiovascular Agents And Endocrines, 6th Edition

Book Summary of Burger's Medicinal Chemistry And Drug Discovery, Volume 3 , Cardiovascular Agents And Endocrines, 6th Edition

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This is Volume 3: Cardiovascular Agents and Endocrines, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Endogenous Vasoactive Peptides, Iron Chelators and Therapeutic Uses, and Fundamentals of Steroid Chemistry and Biochemistry.

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Medicinal chemistry patrick

Graham L. Patrick - An Introduction to Medicinal Chemistry, 4th Edition

Oxford University Press | 2009 | ISBN: 0199234477 | Pages: 752 | DJVU | 21.2 MB

Product Description

The average person in the UK will take more than 14,000 pills over the course of their life, yet few people consider the long road of development that has made that drug work without being toxic. An Introduction to Medicinal Chemistry presents the field in an engaging style that is very accessible to students.

Medicinal chemistry is a fast-moving field whose continuous new developments have far-reaching implications for world health. As such, this text presents a complete course in medicinal chemistry, from first principles of drug action, to design and development, to specific drugs from HIV inhibitors to painkillers.

The book builds on the history of drug development, but does not assume much background knowledge. The focus is on building upon the understandings of the molecular function of drugs, and from there, taking a broad overview of the topical issues and most frequently used techniques.

An Introduction to Medicinal Chemistry remains a leading text for the growing number of medicinal chemistry courses internationally, especially as modules in medical chemistry become a more popular option on chemistry courses. With enhanced attention to the pedagogical details such as key points and boxes, as well as having specific case studies highlighted in distinct sections, Patrick's new edition enables a full understanding of the subject and a clear idea of where the field is heading.

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Advanced Practical Medicinal Chemistry

Advanced Practical Medicinal Chemistry by Ashutosh kar

|PDF|2.97Mb|

The Present Compendium On Advanced Practical Medicinal Chemistry Is Designed Specifically To Serve As A Text-Cum-Reference Book Not Only Intended For The Advanced Undergraduate And Graduate Students Of Pharmacy Specializing In Pharmaceutical Chemistry But Also For The Bulk-Drug Industrial Researchers And Academics Who Work Intimately With Medicinal Compounds. It Mainly Comprises Of Four Comprehensive Chapters. First Chapter Is Entirely Devoted To Safety In Chemical Laboratory, Which Is An Absolute Must For Each Medicinal Chemist. Second Chapter Is On Drug Synthesis And Concentrates On Three Vital Aspects, Namely : Conceptualization Of A Synthesis, Reaction Variants, And Stereochemistry. Third Chapter Exclusively Deals With Performing The Reactions And Entails The Wide Range Of Latest Laboratory Techniques Used In A Good Chemical Laboratory To Facilitate Synthesis Of Drugs.Fourth Chapter Is Particularly Focused And Earmarked To Synthesis Of Medicinal Compounds, And Essentially Include Various Cardinal Aspects, Such As :Types Of Chemical Reactions, Organic Name Reactions (Onrs), And Selected Medicinal Compounds. A Galaxy Of Eighty Carefully Chosen Medicinal Compounds Have Been Presented In Anoriginal-Unique-Style Comprising Of : Chemical Structure-Synonym (S)/Chemical Name(S)-Theory-Chemicals Required-Procedure-Precautions- Recrystallizatio-Theoretical Yield/Practical Yield-Physical Parameters-Uses, And -Questions For Viva-Voce.It Is Hoped That Advanced Practical Medicinal Chemistry Would Certainly Help To Bridge Existing Gap And Fill Up The Long Needed Vacuum In The Synthesis Of Drugs In Pharmaceutical Chemistry Departments, Academics And Bulk-Drug Industries, And May Provide The Basis For Meaningful Productive Group Discussions Of Synthetic Problems On A Broader Perspective.

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Handbook of Spectroscopic Data: Chemistry - UV,IR,PMR,CNMR and Mass Spectroscopy

B. Mistry, "Handbook of Spectroscopic Data: Chemistry - UV,IR,PMR,CNMR and Mass Spectroscopy". 

Oxford Book Company | 2009 | ISBN: 8189473867, 1441660852 | 250 pages | PDF | 6.6 MB

"For any organic chemists intending to gain information about a substance, techniques such as ultraviolet, infrared, nuclear magnetic resonance and mass spectra copy are important ones. This book envisages in it much useful spectral data in table and charts. For graduate and post-graduate students and organic research chemist who are not spectro scopists, the book can be a valuable reference for the interpretation of most spectra. In most cases, the organic chemist should be able to interpret a spectrum using these compilations of data without having to search through more detailed texts in the areas." 

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Foyes principles of medicinal chemistry

The Sixth Edition of this well-known text has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. Emphasis is on patient-focused pharmaceutical care and on the pharmacist as a therapeutic consultant, rather than a chemist.

A new disease state management section explains appropriate therapeutic options for asthma, chronic obstructive pulmonary disease, and men’s and women’s health problems. Also new to this edition: Clinical Significance boxes, Drug Lists at the beginning of appropriate chapters, and an eight-page color insert with detailed illustrations of drug structures.

NEW TO THIS EDITION: case studies from previous editions and answers to this edition’s case studies will be available online at thePoint. New section on Disease State Management (Part IV) helps students understand how asthma, chronic obstructive pulmonary disease, and women’s and men health issues can be treated with appropriate therapeutic options. 8-page color insert contains detailed illustrations of drug structures covered within the text. Clinical Significance boxes show students how the content in each of the chapters relates to effective pharmaceutical care. Drug Lists at the beginning of appropriate chapters are bulleted lists that provide students with a summary of the drugs covered within the chapter.

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Synthesis of Essential Drugs

Ruben Vardanyan / Victor Hruby, «Synthesis of Essential Drugs»Â
Elsevier Science | ISBN 0444521666 | 2006-04-11 | 634 pages | PDF | 3.5 Mb 

This book represents an effort to express a long overdue need of compiling information which has been accumulated over the course of more than 30 years of our work in the area of the synthesis of medicinal drugs. Our effort fills obvious gaps that exist in the literature of drug synthesis.

The synthesis of various groups of drugs are presented in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind - to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists.

Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed description of methods for their synthesis.

Of the thousands of drugs existing on the pharmaceutical market, we mainly discuss generic drugs that are included in the WHO's "Essential List of Drugs."

For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms.

This book will provide the kind of information that will be of interest to those who work, or plan to begin work in the captivating areas of biologically active compounds and the synthesis of medicinal drugs.

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White s Handbook of Chlorination and Alternative Disinfectants, Fifth Edition

White's Handbook of Chlorination and Alternative Disinfectants, Fifth Edition
 2007 | 1062 pages | ISBN:0470180986  | PDF | 5.94 Mb

Since the publication of the Fourth Edition of White's Handbook of Chlorination and Alternative Disinfectants more than ten years ago, the water industry has made substantial advances in their understanding and application of chlorine, hypochlorite, and alternative disinfectants for water and wastewater treatment. This Fifth Edition, with its extensive updates and revisions, reflects the current state of the science as well as the latest practices.  

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Boiler Water Treatment, Principles and Practice, Vol. 1&2

Boiler Water Treatment, Principles and Practice, Vol. 1&2.

By Colin Frayne

• Publisher: Chemical Publishing Company
• Number Of Pages: 400
• Publication Date: 2002-09-25
• ISBN-10 / ASIN: 0820603716
• ISBN-13 / EAN: 9780820603711

Product Description:

Colin Frayne, the author of "Cooling Water Treatment, Principles and Practice" (available at amazon.com) has written this comprehensive reference which is the most practical field guide available on steam and boiler water treatment.

In this two-volume handbook, Frayne analyzes the whole spectrum of boiler systems, including those used in residential complexes, commercial and institutional buildings, and industrial facilities. The breadth of the book covers:

All types of boilers plants, from small cast iron units to large utility and nuclear power plant

- Boiler subsystems, appurtenances, and auxiliaries

- Boiler maintenance and troubleshooting, fuel treatments, combustion gas analysis, pre-treatment processes.

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Cooling Water Treatment: Principles and Practice

Cooling Water Treatment: Principles and Practice.

By Colin Frayne

• Publisher: Chemical Publishing Company
• Number Of Pages: 512
• Publication Date: 2001-01-01
• ISBN-10 / ASIN: 0820603708
• ISBN-13 / EAN: 9780820603704

Product Description:

COOLING WATER TREATMENT, PRINCIPLES AND PRACTICE Through a practical and international approach, this comprehensive reference addresses modern theory, practice, management, purchasing and marketing of cooling water systems, in one volume. This handbook analyzes: - Factors that may compromise and interfere with the optimal functioning and management of cooling water systems. - Treatments, including specialty chemicals, formulations, programming and pre-treatment equipment. - Elements influencing cooling water marketing efforts as well as purchasing decisions. Chapters: 1. Cooling System and Heat Exchange Essentials; 2. Makeup Water Sources and their Impurities; 3. Makeup Water Pretreatment Processes 4. Corrosion, Fouling, and Deposition; 5. Chemical Treatments and Programs for Cooling Water; 6. Microbiological Control Programs; 7. Buying and Selling Cooling Water Programs; 8. Surveys, Inspections, and Cooling Water Program Selection; 9. Managing Cooling Water Programs; 10. Monitoring and Control. These titles may also pair well with this book: 0-8206-0253-1 Microbiology of Cooling Water 0-8206-0298-1 The Chemical Treatment of Cooling Water, 2nd Edition 0820603775 The Chemical Treatment of Boiler Water Other titles by author Colin Frayne: 0-8206-0371-6 Boiler Water Treatment, Principles and Practice, Vol. I 0-8206-0400-3 Boiler Water Treatment, Principles and Practice, Vol. II.

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Principles of Instrumental Analysis

Principles of Instrumental Analysis.

By Douglas A. Skoog, F. James Holler, Stanley R. Crouch

• Publisher: Brooks Cole
• Number Of Pages: 1039
• Publication Date: 2006-12-06
• ISBN-10 / ASIN: 0495012017
• ISBN-13 / EAN: 9780495012016

Product Description:

PRINCIPLES OF INSTRUMENTAL ANALYSIS places an emphasis on the theoretical basis of each type of instrument, its optimal area of its sensitivity, its precision, and its limitations.You'll also learn about elementary analog and digital electronics,, and treatment of analytical datA. Visit the companion website for tutorials on instrumental methods, Excel of data analysis and simulations of analytical techniques to help you visualize important concepts in this course, and selected papers from the chemical literature to stimulate interest and provide background information for study.

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Advanced Structural Inorganic Chemistry

Advanced Structural Inorganic Chemistry.
Publisher: Oxford University Press | ISBN: 0199216940 | edition 2008 | PDF | 688 pages | 12 mb

A revised and updated English version of a postgraduate textbook based on teaching. The term "inorganic" is used in a broad sense as the book covers the structural chemistry of representative elements (including carbon) in the Periodic Table, organometallics, coordination polymers, host-guest systems and supramolecular assemblies.

Part I of the book reviews the basic bonding theories, including a chapter on computational chemistry. Part II introduces point groups and space groups and their chemical applications. Part III comprises a succinct account of the structural chemistry of the elements in the periodic table. It presents structure and bonding, generalizations of structural trends, crystallographic data, as well as highlights from the recent literature.

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Nanoscale Materials in Chemistry

Nanoscale Materials in Chemistry.

2007 | 798 pages | ISBN:0470222700 | PDF | 8 Mb

This extensive text provides twenty-two revised chapters on the preparations, applications, and characterization as well as the environmental and toxicological aspects of nanoscale materials, with an emphasis on the chemistry component.

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Green Chemistry in the Pharmaceutical Industry

Green Chemistry in the Pharmaceutical Industry.
Publisher: Wiley-VCH | 2010 | PDF | 388 pages | ISBN: 3527324186 | 5.8Mb

Edited by three of the world's leading pharmaceutical scientists, this is the first book on this important and hot topic, containing much previously unpublished information. As such, it covers all aspects of green chemistry in the pharmaceutical industry, from simple molecules to complex proteins, and from drug discovery to the fate of pharmaceuticals in the environment. Furthermore, this ready reference contains several convincing case studies from industry, such as Taxol, Pregabalin and Crestor, illustrating how this multidisciplinary approach has yielded efficient and environmentally-friendly processes. Finally, a section on technology and tools highlights the advantages of green chemistry.

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The Chemistry of Pincer Compounds

The Chemistry of Pincer Compounds.

Elsevier Science | ISBN: 0444531386 | 2007-07-23 | PDF | 470 pages | 9.7 MB

Pincer complexes are formed by the binding of a chemical structure to a metal atom with at least one carbon-metal bond. Usually the metal atom has three bonds to a chemical backbone, enclosing the atom like a pincer. The resulting structure protects the metal atom and gives it unique properties.

The last decade has witnessed the continuous growth in the development of pincer complexes. These species have passed from being curiosity compounds to chemical chameleons able to perform a wide variety of applications. Their unique metal bound structures provide some of the most active catalysts yet known for organic transformations involving the activation of bonds. The Chemistry of Pincer Compounds details use of pincer compounds including homogeneous catalysis, enantioselective organic transformations, the activation of strong bonds, the biological importance of pincer compounds as potential therapeutic or pharmaceutical agents, dendrimeric and supported materials.

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