Essentials Pharmaceutical Chemistry

Product Description

It covers the core information required by pharmacy students to understand the action of modern drugs on the human body.The third edition is larger than the previous edition and includes a new chapter on licensing of drugs and medicines which describes the make up and function of important committees such as the Commission of Human Medicines and the British Pharmacopoeia Commission. This includes material that is within the public domain and explains the process of getting a drug to market.The majority of the chapters include more worked examples/tutorial examples and the chapter on Analytical spectroscopy has been updated to include "qualitative" spectroscopic methods especially NMR, mass spectroscopy and some IR and the chapter on Stability of drugs and medicines has been updated to include a major section on "prodrugs" which are inactive compounds designed to decompose within the body to release the active moiety.

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Handbook of Drugs in Intensive Care: An A - Z Guide - 2010 Edition

Handbook of Drugs in Intensive Care: An A - Z Guide - 2010 Edition

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The fourth edition of this compact, practical pocketbook provides easy access for the reader with an A-Z listing of every drug and accompanying advice on its correct administration and potential adverse effects. It is an invaluable resource for all healthcare professionals working in the intensive care setting.

Numerous treatment options are available to intensive care staff; this requires detailed knowledge of routes of administration and contra-indications to use in certain clinical conditions. Now in its fourth edition, this concise, practical handbook to drugs and prescribing for intensive care gives up-to-date advice on established drugs as well as providing advice on those recently approved. The book is divided into two sections: an A-Z guide to many of the drugs available, with concise information on each drug, including uses, limitations, administration directions and adverse effects. The second section contains topics relevant to the critically ill patients, including factors that may affect drug prescribing and management of medical emergencies. There is also a key data section showing weight conversions, BMI and corresponding dosage calculations, and an invaluable chart indicating drug compatibility for IV administration. This is an invaluable resource for doctors, nurses, and pharmacists caring for critically ill patients.

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Burger's Medicinal Chemistry And Drug Discovery, Volume 6, Nervous System Agents, 6th Edition

Book Summary of Burger's Medicinal Chemistry And Drug Discovery, Volume 6, Nervous System Agents, 6th Edition

Product Description:

This is Volume 6: Nervous System Agents, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Alzheimer's Disease: Search for Therapeutics, Cognition Enhancers and Drugs to Treat Eating and Body Weight Disorders. 

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Burger's Medicinal Chemistry And Drug Discovery, Volume 5, Chemotherapeutic Agents, 6th Edition

Burger's Medicinal Chemistry And Drug Discovery, Volume 5, Chemotherapeutic Agents, 6th Edition

Product description

This is Volume 5: Chemotherapeutic Agents, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Molecular Biology of Cancer, Synthetic Anti-angiogenic Agents and Selective Toxicities. 

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Burger's Medicinal Chemistry And Drug Discovery, Volume 4, Autocoids, Diagnostics, And Drugs From New Biology, 6th Edition

Book Summary of Burger's Medicinal Chemistry And Drug Discovery, Volume 4, Autocoids, Diagnostics, And Drugs From New Biology, 6th Edition

Product description

This is Volume 4: Autocoids, Diagnostics, and Drugs from New Biology, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Peptide and Protein Hormones, Peptide Neurotransmitters, and Therapeutic Agents, Vitamins and SNPs: Single Nucleotide Polymorphisms and Pharmacogenomics. 

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Burger's Medicinal Chemistry And Drug Discovery, Volume 3 , Cardiovascular Agents And Endocrines, 6th Edition

Book Summary of Burger's Medicinal Chemistry And Drug Discovery, Volume 3 , Cardiovascular Agents And Endocrines, 6th Edition

Product Description:

This is Volume 3: Cardiovascular Agents and Endocrines, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Endogenous Vasoactive Peptides, Iron Chelators and Therapeutic Uses, and Fundamentals of Steroid Chemistry and Biochemistry.

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Burger's Medicinal Chemistry And Drug Discovery, Volume 2, Drug Discovery And Drug Development, 6th Edition

Book Summary of Burger's Medicinal Chemistry And Drug Discovery, Volume 2, Drug Discovery And Drug Development, 6th Edition

This Sixth Edition of Burger's Medicinal Chemistry and Drug Discovery has been expanded to six volumes: 

Volume 1: Drug Discovery

Volume 2: Drug Discovery and Drug Development

Volume 3: Cardiovascular Agents and Endocrines

Volume 4: Autocoids, Diagnostics, and Drugs from New Biology

Volume 5: Chemotherapeutic Agents

Volume 6: Nervous System Agents 

This is Volume 2: Drug Discovery and Drug Development, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Combinational Chemistry and Multiple Parallel Synthesis, High Throughput Pharmacology, and Retrometabolism-Based Drug Design and Targeting.

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BURGER'S MEDICINAL CHEMISTRY AND DRUG DISCOVERY, Volume 1, Drug Discovery, 6th Edition

Book Summary of Burger's Medicinal Chemistry And Drug Discovery, Volume 1, Drug Discovery, 6th Edition

Product description

"An essential addition to the libraries of any medicinal chemist . . . an outstanding work . . . highly praised as a fountain of information in drug studies and research."

-Journal of Medicinal Chemistry on the Fifth Edition 

This new edition of Dr. Alfred Burger's internationally celebrated classic helps researchers acquaint themselves with both traditional and state-of-the-art principles and practices governing new medicinal drug research and development. Completely updated and revised to reflect the many monumental changes that have occurred in the field, this latest edition brings together contributions by experts in a wide range of related fields to explore recent advances in the understanding of the structural biology of drug action, as well as cutting-edge technologies for drug discovery now in use around the world. 

This Sixth Edition of Burger's Medicinal Chemistry and Drug Discovery has been expanded to six volumes: 

Volume 1: Drug Discovery

Volume 2: Drug Discovery and Drug Development

Volume 3: Cardiovascular Agents and Endocrines

Volume 4: Autocoids, Diagnostics, and Drugs from New Biology

Volume 5: Chemotherapeutic Agents

Volume 6: Nervous System Agents 

This is Volume 1: Drug Discovery, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Virtual Screening, Bioinformatics and Chemical Information Computing Systems in Drug Discovery.

Next volume will be in next post

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Medicinal chemistry patrick

Graham L. Patrick - An Introduction to Medicinal Chemistry, 4th Edition

Oxford University Press | 2009 | ISBN: 0199234477 | Pages: 752 | DJVU | 21.2 MB

Product Description

The average person in the UK will take more than 14,000 pills over the course of their life, yet few people consider the long road of development that has made that drug work without being toxic. An Introduction to Medicinal Chemistry presents the field in an engaging style that is very accessible to students.

Medicinal chemistry is a fast-moving field whose continuous new developments have far-reaching implications for world health. As such, this text presents a complete course in medicinal chemistry, from first principles of drug action, to design and development, to specific drugs from HIV inhibitors to painkillers.

The book builds on the history of drug development, but does not assume much background knowledge. The focus is on building upon the understandings of the molecular function of drugs, and from there, taking a broad overview of the topical issues and most frequently used techniques.

An Introduction to Medicinal Chemistry remains a leading text for the growing number of medicinal chemistry courses internationally, especially as modules in medical chemistry become a more popular option on chemistry courses. With enhanced attention to the pedagogical details such as key points and boxes, as well as having specific case studies highlighted in distinct sections, Patrick's new edition enables a full understanding of the subject and a clear idea of where the field is heading.

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Essentials of Medical Pharmacology by Tripathi

Essentials of Medical Pharmacology by K.D Tripathi

Jaypee Publishers | 6th Edition | ISBN:  9788184480856 | Pharma Dost  | PDF | 142 MB  

"Essentials of Medical Pharmacology provides broad coverage from principles of drug action to basis of their therapeutic use and skill of rational selection of drugs. Mechanisms of drug action are explained in a simplified manner. Essential pharmacodynamic, pharmacokinetic and dosage form information is included to enable prescribing with understanding and confidence.

Highlights of the sixth edition are:

• Extensively revised and updated chapters to include recently introduced drugs, published information and therapeutic practices.
• New chapter on aspects of therapeutics including principles of rational use of medicines, elements of evidence based medicine and process of new drug development.
• Comprehensive chapter on drug interactions and an additional appendix on prescribing in pregnancy.
• Latest therapeutic guidelines from eminent professional bodies, WHO, National Health Programmes in relevant areas.
• Reinforcement of evidence based use of medicines by reference to results of credible drug trials.
• Emphasis on the profile of diseases and drug use in India and other tropical countries.
• A highly structured, systematic, user friendly and attractive layout with enriched illustrations

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Advanced Practical Medicinal Chemistry

Advanced Practical Medicinal Chemistry by Ashutosh kar

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The Present Compendium On Advanced Practical Medicinal Chemistry Is Designed Specifically To Serve As A Text-Cum-Reference Book Not Only Intended For The Advanced Undergraduate And Graduate Students Of Pharmacy Specializing In Pharmaceutical Chemistry But Also For The Bulk-Drug Industrial Researchers And Academics Who Work Intimately With Medicinal Compounds. It Mainly Comprises Of Four Comprehensive Chapters. First Chapter Is Entirely Devoted To Safety In Chemical Laboratory, Which Is An Absolute Must For Each Medicinal Chemist. Second Chapter Is On Drug Synthesis And Concentrates On Three Vital Aspects, Namely : Conceptualization Of A Synthesis, Reaction Variants, And Stereochemistry. Third Chapter Exclusively Deals With Performing The Reactions And Entails The Wide Range Of Latest Laboratory Techniques Used In A Good Chemical Laboratory To Facilitate Synthesis Of Drugs.Fourth Chapter Is Particularly Focused And Earmarked To Synthesis Of Medicinal Compounds, And Essentially Include Various Cardinal Aspects, Such As :Types Of Chemical Reactions, Organic Name Reactions (Onrs), And Selected Medicinal Compounds. A Galaxy Of Eighty Carefully Chosen Medicinal Compounds Have Been Presented In Anoriginal-Unique-Style Comprising Of : Chemical Structure-Synonym (S)/Chemical Name(S)-Theory-Chemicals Required-Procedure-Precautions- Recrystallizatio-Theoretical Yield/Practical Yield-Physical Parameters-Uses, And -Questions For Viva-Voce.It Is Hoped That Advanced Practical Medicinal Chemistry Would Certainly Help To Bridge Existing Gap And Fill Up The Long Needed Vacuum In The Synthesis Of Drugs In Pharmaceutical Chemistry Departments, Academics And Bulk-Drug Industries, And May Provide The Basis For Meaningful Productive Group Discussions Of Synthetic Problems On A Broader Perspective.

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Introduction to Medicinal Chemistry

Introduction to Medicinal Chemistry: How Drugs Act and Why by: Alex Gringauz

Publisher: Wiley-VCH | ISBN: 0471185450 | 1996-12-27 | Pages: 736 | DJVU | 23 MB

This work brigdges the compartmentalized undergraduate organic and biochemistry and biology subjects to the pharmacology and the clinical areas a modern pharmacy practice requires. The changes and constantly increasing responsibilities of today's pharmacist have dictated a restructuring of the pharmacy curriculum, including individual course content. This book reflects and addresses these developments. This is a well-written work that covers most major areas of pharmaceutical research. The text is presented in a logical and concise fashion being divided into chapters based upon therapeutic topic. This makes the work very useful for teaching a course in medicinal chemistry since therapeutic areas can be separately covered without having to make use of the entire book which overall contains a tremendous amount of information. This book is a significant contribution to understanding what medicinal chemistry is and how this science is used to develop new therapeutic agents.

Basic Considerations of Drug Activity.

Mechanisms of Drug Action.

Drug Metabolism and Inactivation.

Anticancer Drugs and Their Mechanism of Action.

Analgetics and Nonsteroidal Antiinflammatory Agents.

Antimicrobial Drugs I. Antimicrobial Drugs II.

Drugs Affecting Cholinergic Mechanisms.

Drugs Affecting Adrenergic Mechanisms.

Drugs and the Cardiovascular Diseases.

Drugs and the Cardiovascular Diseases II.

Psychoactive Drugs--Chemotherapy of the Mind.

Histamine Antagonists and Local Anesthetics.

Steroids.

New Developments and New Problems.

Index.

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MCQs in Biochemistry

MCQs in biochemistry by G.Vidyasagar

Book Details

Title:	MCQs in Biochemistry
Publisher:	New Age International
Author:	G Vidya Sagar
Edition Number:	1
EAN:	9788122423570
No. of Pages:	300

Medical and Paramedical graduates aspiring for higher education planning to take PG ought to appear in entrance examinations. These entrance examinations are usually patterned in objective type. Biochemistry forms an integral part of curriculum of medical and paramedical courses. It is an important subject and deals with various Chemical, Biochemical, and Physiological reactions and processes that take place inside a living system. Quite a large number of MCQs appear in PG medical and paramedical competitive examinations in this subject. Multiple Choice Questions (MCQs) test a candidate`s ability to apply his knowledge gained during regular class work in the subject. 

Framing a questions paper based on MCQs is time consuming and evaluation of answers is not subjective and biased but on based on merit. Several universities now-a-days are adopting MCQ pattern for their examination system. This system of evaluation can be computerized and human bias can be eliminated to a greater extent. The Medical Council of India in their latest recommendations on the medical education and examination have stipulated that part of the question paper should be objective type based. The Rajiv Gandhi University of Health Sciences, Karnataka, the Tamil Nadu MGR Medical University, Tamil Nadu and the Rajasthan University of Health Sciences, Rajasthan also use the MCQ pattern in all their undergraduate and PG programmes of Medial and Paramedical courses. 

The quick solution books presently available for this subject in the market do not cover the subject in an integrated way. Acquiring knowledge becomes simple if all the required information is made available at one place. 

The MCQs in the book have been prepared with great care and after an exhaustive and extensive study of pattern of multiple choice questions in the subject. The questions are precise and clear enabling the reader to make correct choice based on his understanding of Biochemistry. 

About the Author(s):

G. Vidya Sagar, is presently working as Director and Principal of Veerayatan Institute of Pharmacy, Mandvi, Kutch (Gujarat) and Dean, Faculty of Pharmaceutical Sciences, KSKV Kachchh University, Bhuj. With a teaching experience of over 20 years, Dr. Vidya Sagar has authored 12 popular textbooks in Pharmaceutical Sciences which have gained wide acclaim. He has 150 review articles and 70 research publications to his credit. 

G. Vidya Sagar is a popular figure in Pharmaceutical Parlance. He is an examiner, paper setter and PG and Ph.D. thesis adjudicator for several Indian Universities. He served as Chairman, Board of Studies (Pharmacy) of Acharya Nagarjuna University, Guntur, A.P. He is an editorial board member of several prestigious journals and chaired many scientific sessions of National and International conferences. He has served as a resource person for various UGC, AICTE and MCI faculty development programmes. His area of research includes Analytical method of development of drugs, Pharmacological and Phytochemical screening of medicinally useful drug plants. 

He is also associated with many professional associations like Indian Pharmacological Society, IPA, IHPA, ISTE, IPGA, APTI and many more. 

This book is his contribution towards a better comprehension and understanding of Biochemistry. 

Contents:

Introduction to Biochemistry 

Carbohydrates and Carbohydrate Metabolism 

Proteins & Protein Metabolism 

Fats & Fatty Acid Metabolism 

Vitamins 

Enzymes 

Mineral Metabolism 

Hormone Metabolism 

Nucleic Acids 

Water & Electrolyte Balance

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The Textbook of Pharmaceutical Medicine

John P. Griffin, "The Textbook of Pharmaceutical Medicine" 

BMJ Books / Wiley-Blackwell | 2009 | ISBN: 1405180358 | 776 pages | PDF | 3.8 MB

The Textbook of Pharmaceutical Medicine is a standard reference for all those working in pharmaceutical medicine and the recognised text for the UK Faculty of Pharmaceutical Medicine Diploma. This is a comprehensive volume covering the processes by which medicines are developed, tested and approved. Regulations for drug development in the UK, EU, USA, Australia and Japan are discussed, providing relevant information for drug approval in the main continents where new drugs are developed.

The chapters are written by leading academics, medical directors and lawyers, providing authoritative and in-depth information for trainees on the Faculty course, and for physicians working in the pharmaceutical industry. As well as thorough updating of the regulatory chapters, the 6th edition includes chapters on these vital new areas:

Paediatric regulation

Ethics

Due diligence and the pharmaceutical physician

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Foyes principles of medicinal chemistry

The Sixth Edition of this well-known text has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. Emphasis is on patient-focused pharmaceutical care and on the pharmacist as a therapeutic consultant, rather than a chemist.

A new disease state management section explains appropriate therapeutic options for asthma, chronic obstructive pulmonary disease, and men’s and women’s health problems. Also new to this edition: Clinical Significance boxes, Drug Lists at the beginning of appropriate chapters, and an eight-page color insert with detailed illustrations of drug structures.

NEW TO THIS EDITION: case studies from previous editions and answers to this edition’s case studies will be available online at thePoint. New section on Disease State Management (Part IV) helps students understand how asthma, chronic obstructive pulmonary disease, and women’s and men health issues can be treated with appropriate therapeutic options. 8-page color insert contains detailed illustrations of drug structures covered within the text. Clinical Significance boxes show students how the content in each of the chapters relates to effective pharmaceutical care. Drug Lists at the beginning of appropriate chapters are bulleted lists that provide students with a summary of the drugs covered within the chapter.

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Synthesis of Essential Drugs

Ruben Vardanyan / Victor Hruby, «Synthesis of Essential Drugs»Â
Elsevier Science | ISBN 0444521666 | 2006-04-11 | 634 pages | PDF | 3.5 Mb 

This book represents an effort to express a long overdue need of compiling information which has been accumulated over the course of more than 30 years of our work in the area of the synthesis of medicinal drugs. Our effort fills obvious gaps that exist in the literature of drug synthesis.

The synthesis of various groups of drugs are presented in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind - to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists.

Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed description of methods for their synthesis.

Of the thousands of drugs existing on the pharmaceutical market, we mainly discuss generic drugs that are included in the WHO's "Essential List of Drugs."

For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms.

This book will provide the kind of information that will be of interest to those who work, or plan to begin work in the captivating areas of biologically active compounds and the synthesis of medicinal drugs.

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Water Properties in Food: Pharmaceutical and Biological Systems: ISOPOW 10

Water Properties in Food, , Pharmaceutical and Biological Systems: ISOPOW 10.

By David S. Reid, Tanaboon Sajjaanantakul, Peter J. Lillford, Sanguansri Charoenrein

• Publisher: Wiley-Blackwell
• Number Of Pages: 804
• Publication Date: 2010-07-06
• ISBN-10 / ASIN: 0813812739
• ISBN-13 / EAN: 9780813812731

Product Description:

This title focuses on the comprehension of the properties of water in foods, enriched by the approaches from polymer and materials sciences, and by the advances of analytical techniques. The International Symposium on the Properties of Water (ISOPOW) promotes the exchange of knowledge between scientists involved in the study of food materials and scientists interested in water from a more basic point of view and the dialogue between academic and industrial scientists/technologists. This comprehensive book covers the topics presented at the 10th ISOPOW held in Bangkok, Thailand in 2007, including water dynamics in various systems, the role of water in functional food and nano-structured biomaterials.

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Pharmaceutical Bioassays: Methods and Applications

Pharmaceutical Bioassays: Methods and Applications.

By Shiqi Peng, Ming Zhao

Publisher: Wiley

Number Of Pages: 497

Publication Date: 2009-11-09

ISBN-10 / ASIN: 0470227605

ISBN-13 / EAN: 9780470227602

Product Description:

The definitive compendium of bioassay procedures and applications

A virtual encyclopedia of key bioassay protocols, this up-to-date, essential resource reviews the methods and applications of bioassays that quantify drug activity and evaluate the validity of pharmacological models.

Demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules, the book covers the evaluation and screening of drug compounds in a wide spectrum of therapeutic categories.

Throughout, the authors use various models to link experimental observations with findings that clarify the effect of drug compounds on cellular biology and measure the pharmacological activity of chemical substances. This provides an important technological platform for successful drug research and clinical therapy, making Pharmaceutical Bioassays an ideal sourcebook for pharmacologists, pharmaceutical and medical researchers, analytical chemists, toxicologists, and students.

Just as a fundamental knowledge of pharmaceutical bioassays is vital to understanding how bioactive agents and new drugs are defined, discovered, and developed, so too is this indispensable reference, which:

Offers a complete reference on pharmaceutical bioassays and their specific applications in the assessment of therapies for cancer, Alzheimer's, diabetes, epilepsy, inflammation, antimalarials, pharmacogenomics, and other major therapeutic areas

Covers bioassays that measure toxicity, including those for chemical toxicity and hepatoxicity—a particularly significant consideration in the development of safe and tolerable medications

Highlights clinically relevant methods, ideas, and techniques to support any pharmaceutical researcher

Suggests guidelines and systems to enhance communication between pharmacologists, chemists, and biologists

Provides an informative analysis of pharmaceutical bioassay technologies and lab applications.

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The Textbook of Pharmaceutical Medicine

The Textbook of Pharmaceutical Medicine.

By John P. Griffin

• Publisher: BMJ Books / Wiley-Blackwell
• Number Of Pages: 776
• Publication Date: 2009-12-14
• ISBN-10 / ASIN: 1405180358
• ISBN-13 / EAN: 9781405180351

Product Description:

The Textbook of Pharmaceutical Medicine is a standard reference for all those working in pharmaceutical medicine and the recognised text for the UK Faculty of Pharmaceutical Medicine Diploma. This is a comprehensive volume covering the processes by which medicines are developed, tested and approved. Regulations for drug development in the UK, EU, USA, Australia and Japan are discussed, providing relevant information for drug approval in the main continents where new drugs are developed.

The chapters are written by leading academics, medical directors and lawyers, providing authoritative and in-depth information for trainees on the Faculty course, and for physicians working in the pharmaceutical industry. As well as thorough updating of the regulatory chapters, the 6th edition includes chapters on these vital new areas:

• Paediatric regulation
• Ethics
• Due diligence and the pharmaceutical physician.

Read More

ACD/ChemSketch 12.0

ACD/ChemSketch is an advanced chemical drawing tool and is the accepted interface into the industry's best NMR and molecular property predictions, nomenclature, and analytical data handling software.

ACD/ChemSketch is also available as freeware, with functionalities that are highly competitive with other popular commercial software packages. The freeware contains tools for tautomer prediction, 2D structure cleaning, 3D optimization and viewing, drawing of polymers, organometallics, and Markush structures - capabilties which are not even included in some of the commercial packages from other software producers. Also included is an IUPAC systematic naming capability for molecules with fewer than 50 atoms and 3 rings. The capabilities of ACD/ChemSketch can be further extended and customized by programming.

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